Canterbury DHB

Context

Second-line Antiemetics

In This Section

Levomepromazine (Methotrimeprazine)

Dexamethasone

Prochlorperazine

Hyoscine (Scopoderm TTS™)

Lorazepam

Ondansetron

Levomepromazine (Methotrimeprazine)

Dexamethasone

See also: Corticosteroids

Prochlorperazine

Hyoscine (Scopoderm TTS™)

Note: Scopoderm TTS™ patches incur a part charge at community pharmacies but if used 'in the control of intractable nausea, vomiting, or inability to swallow saliva in the treatment of malignancy or chronic disease', a special authority number can be applied for. Often there are supply problems which cause lack of availability. See PHARMAC website.

Lorazepam

Ondansetron

The serotonin (5HT3) antagonists, e.g., ondansetron, have proven benefit in chemotherapy and radiation induced emesis BUT are NOT generally prescribed in the treatment of vomiting in Palliative Care patients due to limited evidence of benefit.

Regular ondansetron use causes significant constipation.

About this Canterbury DHB document (4088):

Document Owner:

Kate Grundy (see Who's Who)

Issue Date:

February 2013

Next Review:

March 2015

Keywords:

Note: Only the electronic version is controlled. Once printed, this is no longer a controlled document. Disclaimer

Topic Code: 4088