Canterbury DHB

Context

Oxycodone

Oxycodone should be prescribed with caution if GFR < 30 mL/ min.

Oxycodone is contraindicated if GFR < 15 mL/min.

Available in four formulations. IR stands for immediate release i.e. fast-acting and CR stands for controlled release:

Oxycodone is similar to morphine in its action and has a similar side effect profile. This drug is more expensive than morphine and there is no clinical evidence to support its use first line. Morphine therefore remains the drug of first choice.

The main indications for use at present are:

Note: When taken orally, oxycodone is more potent than morphine - 10 mg oral morphine @ 5 mg oral oxycodone.

See:

About this Canterbury DHB document (4060):

Document Owner:

Kate Grundy (see Who's Who)

Issue Date:

March 2016

Next Review:

March 2018

Keywords:

Note: Only the electronic version is controlled. Once printed, this is no longer a controlled document. Disclaimer

Topic Code: 4060